When deploying Intune, you have 2 options. In the following table you see the difference between them :
| Stand-alone | Hybrid | |
| Administration with ConfigMgr | No | Yes |
| Supported Devices | IOS 6+, Android 4+, Windows Workstations, Windows RT, Windows Phone 8+ | IOS 6+, Android 4+, Windows Workstations and Servers, Windows RT, Windows Phone 8+, Linux Servers, Mac OSX |
| Maximum nr of managed device count | 50.000 mobile devices, 7000 mixed mobile devices and PC’s | 50000 with ConfigMgr, 100.000 with a dedicated ConfigMgr primary site |
| On-premises infrastructure required | No | Yes |
| Extensible and customizale (inventory, reporting, third-party) | No | Yes |
| Simple web Console accessible from anywhere | Yes | No |
| Requires client connectivity to the internet | Yes | No |
| Integrated Operating System Deployment | No | Yes |
| Retire and wipe devices | Yes | Yes |
| Full-featured app deployment | Yes | Yes |
| Software Updates | Yes | Yes |
| Endpoint protection | Yes | Yes |
| App-V Integration | No | Yes |
| Software Metering | No | Yes |
| Rapid updates to features and capabilities with no upgrades required | Yes | Using ConfigMgr 2012R2 |